The most common adverse reactions are skin irritation symptoms (burning sensation and itching, redness, pain, paraesthesia and rash) at the site of application.
As a rule, they are expressed moderately and disappear within the first week after the start of treatment.
Often there is alcohol intolerance (redness person or symptoms of skin irritation after drinking).
patients applying testosterone blend 250mg , there is an increased risk of folliculitis, acne and herpes infection.
As the frequency of occurrence of adverse reactions are divided into very frequent . Within each group, adverse reactions are presented in order of importance. General disorders and local reactions Very common: burning and itching at the application site. Common: feeling of warmth, redness, pain, irritation, rash in the area of application.Infections Common: herpes infection (simple herpes of the face and lips, varitselliformnaya rash galoshes). skin and subcutaneous tissue Common: folliculitis, itching. Infrequent: acne. Nervous systemFrequent: paresthesia, hypersensitivity. Metabolism and eating habits Frequent: alcohol intolerance (facial flushing or skin irritation symptoms after drinking alcohol drinks). Over the entire period of observation of the drug have been reported isolated cases of rosacea, malignancy (skin and other types of lymphoma, skin cancer).
is not mentioned. When applied topically overdose
Ingestion need to take common action which include monitoring of vital body functions and the monitoring of the general state.
Stimulation of vomiting or gastric lavage is not recommended.
Interaction with other medicinal products
Tacrolimus is not metabolised in the skin, eliminating the risk of drug interactions in the skin, which can affect its metabolism. Since systemic absorption of tacrolimus when used in the form of an ointment is minimal interaction with inhibitors (erythromycin, itraconazole, ketoconazole, diltiazem, etc..), While the application testosterone blend 250mg is unlikely, but can not be completely ruled out in patients with extensive lesions, and / or erythroderma.
Influence of Protopic ointment on the vaccination efficacy have not been studied. However, because of the potential effectiveness of risk reduction, vaccination must take place before the application of ointments or 14 days after the last use of Protopic ointment. In the case of live attenuated vaccines during this period should be increased to 28 days, otherwise it is necessary to consider the use of alternative vaccines.
The ability to share with other external agents, systemic corticosteroids and immunosuppressive agents has not been studied.
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Ointment Protopic should not be used in patients with congenital or acquired immunodeficiencies or in patients who are taking immunosuppressive drugs.
During the application of an should avoid contact with the skin to sunlight, solarium, treatment with UV rays B or A in combination with psoralen (PUVA-therapy).
ointment Protopic should not be used to treat the affected areas, which are considered to be potentially malignant or pre-malignant.
for 2 hours on areas of the skin, which was applied , you can not use emollients.
Efficacy and safety in the treatment of infected atopic dermatitis has not been evaluated. Where there is evidence of infection before prescribing testosterone blend 250mg is necessary to conduct appropriate therapy. The use of Protopic ointment may be associated with an increased risk of herpes infection. Where there is evidence of herpes infection should be individually weigh the benefits and risks of Protopic.
In the presence of lymphadenopathy is necessary to examine the patient before treatment and monitor them during the application of ointment. If there is no obvious cause of lymphadenopathy or in the presence of symptoms of acute infectious mononucleosis is necessary to stop the use of Protopic ointment.
It is necessary to avoid ointments contact with eyes and mucous membranes (in case of accidental contact with the ointment must be carefully removed and / or washed with water).
Do not apply under occlusive dressings and wearing tight clothes airtight.
Just like with any other topical medicinal product, patients should wash their hands after applying the ointment, except in cases where the ointment is applied to the area of hands for therapeutic purposes. how much to inject for weight loss
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